AMD Threadripper pro 3995wx Processor
Nvidea RTX3090 GPU or 3080Ti.
I believe these GPU’s are SLI capable meaning you can install more than 1 and hook them together. Finding one is another story.
Ram is also going to be a concern. 64gb is what i would shoot for. Spending this kind of money I may consider hiring a pro to build it. Keeping it cool is going to be important.